BIOMARKER IDENTIFICATION, THERAPY DISCOVERY AND TARGET VALIDATION
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Projects

1) Therapy-induced breast cancer cell vulnerabilities in novel co-culture/co-xenograft models of minimal residual disease.

Lab Members: Guth (postdoc), Hamalian (grad), Meade (grad), Shisgal (grad), Duell (undergrad), Aguayo (undergrad), Geller (technician)

Current Collaborators: Brugge, Sorger, Gygi and Tchou

 

2) ITGA1-dependent mechanisms of stress resistance and progression in pancreatic cancer.

Lab Members: Kim (grad), Canahui (undergrad) and Geller (technician)

Current Collaborators: Bouvet and Doebler

 

3) Mechanisms of stress-induced stem cell secretome/metabolome composition and function during tissue regeneration.

Lab Members: Duell (undergrad) and Geller (technician)

Current Collaborators: Panopoulos and Gray

 

4) Targeting HDAC6/DHPS synergism in TGFβ-mediated breast cancer progression.

Lab Members: Guth (postdoc), Runa (postdoc), Kutscher (undergrad) and Geller (technician)

Current Collaborators: Brugge and Bui