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BIOMARKER IDENTIFICATION, THERAPY DISCOVERY AND TARGET VALIDATION
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Projects

1) Stroma-tumor intercellular regulation of breast cancer cell heterogeneity and targeted therapy resistance

Collaborators: Brugge (Harvard), Spike (Huntsman), Bui (UCSD) and Tchou (U. Penn.)

 

2) Novel mechanisms of collagen-mediated stress resistance within the pancreatic cancer microenvironment

Collaborators: Bouvet (UCSD), Doebler (Claremont BioSolutions) and Boyce (Duke)

 

3) Development of effective therapeutic strategies for blocking metastatic progression in breast cancer

Collaborators: Brugge (Harvard) and Bui (UCSD)

 

4) Mechanisms of regulating stem cell secretome/metabolome composition and function during tissue regeneration/repair.

Collaborators: Panopoulos (Notre Dame) and Spike (Huntsman Cancer Center)